Two stoners seeking zombie brains to fertilize their weed crop get captured by a gay flesh-eater with dreams of global domination, and fight for their lives alongside a tough-as-nails farm-girl with a talent for building zombie death weapons in this gore soaked stoner comedy that doesn't skimp on the grey matter. A meteorite carrying a highly contagious zombie virus has crashed into planet Earth, transforming much of the population into undead gut-munchers and leaving the few survivors stranded in tightly-controlled safe zones. In order to beat the boredom of living in a post-apocalyptic society devoted stoners Edwin and Tommy spend most of their time growing marijuana. And in their endless quest to develop the most potent strain possible, the two ganja-loving gardeners discover that zombie brains make the perfect fertilizer. But there's on big problem: the government has sealed of the areas where the dead still walk, so in order to keep their harvest coming Edwin and Tommy will have to brave the wastelands. Unfortunately for the perpetually-stoned duo, flaming zombie Alex has amassed an army of walking corpses in preparation to reclaim the planet, and quickly captures the wayward horticulturalists. Later, Edwin and Tommy stage a daring escape and cross paths with the pretty-but-deadly Leah. A fearless survivor with a talent for creating weapons, Leah decides there's no time like the present to join the war against the undead, and begins construction on a contraption that will tear Alex and his shambling battalion of brain-eaters limb from rotten limb.